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KMID : 0811720140180050359
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Korean Journal of Physiology & Pharmacology
2014 Volume.18 No. 5 p.359 ~ p.363
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MicroRNA-1 in Cardiac Diseases and Cancers
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Li Jian-Zhe
Dong Xiao-Min
Wang Zhong-Ping
Wu Jian-Hua
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Abstract
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MicroRNAs (miRs) are endogenous ?22-nt non-coding RNAs that participate in the regulation of gene expression at post-transcriptional level. MiR-1 is one of the muscle-specific miRs, aberrant expression of miR-1 plays important roles in many physiological and pathological processes. In this review, we focus on the recent studies about miR-1 in cardiac diseases and cancers. The findings indicate that miR-1 may be a novel, important biomarker, and a potential therapeutic target in cardiac diseases and cancers.
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KEYWORD
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Cancers, Cardiac diseases, MicroRNA-1
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